Just The Cheese Crunchy Baked Cheese Low In Carbohydrates! 100% Natural Cheese for 100% Cheese Taste The Specialty Cheese Company has found a 17-step baking process that makes natural cheese into a crunchy snack! Since there are no carbohydrates in cheese, these new baked cheeses are an ideal addition to a low carbohydrate diet. No refrigeration required! They simply take slices of natural cheeses, season and gently bake them to crisp, delicious perfection. Nothing else added. And since the patented baking process preserves cheese's natural nutrients, Just The Cheese Crunchy Baked Cheese are Protein and Calcium rich! Each piece of Just The Cheese Crunchy Baked Cheese is a golden gem of natural cheese the first crunches and then melts in your mouth. Just the Cheese Crunchy Baked Cheese pieces make sensational snacks, creative crumbles for soups and salads, and are delicious with your favorite dips. INGREDIENTS: Natural Cheese (Milk, salt, enzymes), spices. Add To Cart Item ID Brand Product Unit Size Retail Price Our Price $200+ Orders** Volume Discounts Buy 19-0901 Specialty Cheese Just The Cheese Chips, Herb 'n Garlic 2 oz. $3.99 $2.59 $2.46 as low as $1.98 Buy 19-0908 Specialty Cheese Just The Cheese Chips, Honey Dijon 2 oz. $3.99 $2.59 $2.46 as low as $1.98 Buy 19-0902 Specialty Cheese Just The Cheese Chips, Jalapeno 2 oz. $3.99 $2.59 $2.46 as low as $1.98 Buy 19-0905 Specialty Cheese Just The Cheese Chips, Nacho 2 oz. $3.99 $2.59 $2.46 as low as $1.98 Buy 19-0907 Specialty Cheese Just The Cheese Chips, Pizza 2 oz. $3.99 $2.59 $2.46 as low as $1.98 Buy 19-0903 Specialty Cheese Just The Cheese Chips, Sour Cream 'n Onion 2 oz. $3.99 $2.59 $2.46 as low as $1.98 Buy 19-0904 Specialty Cheese Just The Cheese Chips, White Cheddar 2 oz. $3.99 $2.59 $2.46 as low as $1.98 Buy 19-0906 Specialty Cheese Just The Cheese Chips, White Cheddar - 25% Lower Sodium Splenda Granular and Packets Splenda is a low calorie sweetener that tastes like sugar and can be used virtually everywhere sugar is used. Splenda is a low calorie sweetener that is made from sugar, so it tastes like sugar. Splenda is the sweetening ingredient that is already used to sweeten many low calorie foods and beverages. Splenda is now available in two forms -- granular, which measures and pours like sugar, as well as in packets to add to your favorite beverages. Please note that due to the inclusion of maltodextrin in Splenda Granular, a cup of Splenda Granular has 96 calories and 24 grams of carbohydrates compared to the 770 calories and 192 grams of carbohydrates found in a cup of sugar. Splenda Packets contain both dextrose and maltodextrin. Though Splenda is still siginificantly lower in carbohydrates than sucrose (sugar), it is not a zero carbohydrate product. Use sparingly with a low carb diet. If you would like to let the manufacturer of Splenda, McNeil Specialty Products Company, know your opinion about their use of maltodextrin and dextrose in their Splenda products, contact them at 1-800-777-5363. Suggested Use: Baking, Diabetic Diets, Sugar Substitute Frequently Asked Questions about SPLENDA (Sucralose) What is SPLENDA ? How is SPLENDA made? Is SPLENDA safe? What advantages does SPLENDA offer versus other sweeteners? Can SPLENDA be used in cooking or baking? How low are the calories in SPLENDA ? Do I have to count SPLENDA as a carbohydrate or sugar in my meal plan? Is SPLENDA safe for children? Can pregnant and breastfeeding women consume SPLENDA? What is the role of SPLENDA in a healthy diet? What types of products might contain SPLENDA ? What is SPLENDA ? SPLENDA is the first and only low-calorie sweetener made from sugar and is the brand name for the sweetening ingredient Sucralose. It can be used in place of sugar to eliminate or reduce calories in a broad range of foods, including beverages, baked goods, desserts, dairy products, syrups, condiments and processed fruits. How is SPLENDA made? SPLENDA is made from sugar (sucrose) by a patented process that replaces three of sugar's hydrogen-oxygen groups with chlorine atoms. This exchange makes the resulting SPLENDA molecule extremely sweet, about 600 times sweeter than sugar, and extremely stable. SPLENDA is so stable that, unlike other sweeteners, it will not break down or lose its sweetness when used in cooking or baking, or when used in beverages, like carbonated soft drinks, which typically have a high acidity. SPLENDA is also unable to be metabolized (broken down) by the body's food-digesting enzymes. This means that SPLENDA has no calories! And better yet, because SPLENDA is made from sugar, it tastes like sugar, so SPLENDA can be used virtually anywhere sugar is used. Try it in all your favorite recipes. Is SPLENDA safe? Yes. SPLENDA has been authorized for use by the FDA for use by all persons and has been safely enjoyed by millions of consumers around the world in places like Canada, Mexico, and Australia. The sweetening ingredient in SPLENDA, sucralose, is one of the most thoroughly tested food additives in history. More than 100 studies on the safety of SPLENDA, designed to meet the highest scientific standards, have been conducted and evaluated over the course of 20 years. SPLENDA doesn't react with other substances in the body and is not broken down in the body. It has no effect on insulin or blood glucose levels and is appropriate for use by anyone wishing to reduce their caloric or sugar intake. Foods containing SPLENDA do not require warning labels or information statements. No one is excluded from using SPLENDA. The safety of SPLENDA has also been confirmed by the regulatory agencies in a growing number of countries around the world. Further, the data from SPLENDA studies were independently evaluated by international experts in a variety of scientific disciplines, including toxicology, oncology, teratology, neurology, hematology, pediatrics, nutrition and others. These experts unanimously concluded that SPLENDA is safe for human consumption. Importantly, comprehensive toxicology studies have clearly demonstrated that SPLENDA does not cause cancer or any other adverse health effects. As a result, SPLENDA is safe even for individuals who consume large amounts of sweetened products on a daily basis. What advantages does SPLENDA offer versus other sweeteners? SPLENDA provides a high quality, sugar-like taste and is exceptionally stable under a broad range of processing, product pH, and temperature conditions. These qualities make it useful as a sugar replacement in virtually every type of food and beverage, including those previously unavailable in a good tasting, low calorie form. Can SPLENDA be used in cooking or baking? Yes! SPLENDA can be used in any cooking and baking recipe. SPLENDA does not lose its sweetness even at the high temperatures associated with cooking and baking. Is SPLENDA safe for children? The use of SPLENDA to sweeten foods and beverages is not hazardous to a young person's health. One should note, however, that foods made with low-calorie sweeteners are not normally a recommended part of a child's diet, since calories are important to a growing child's body. Can pregnant and breastfeeding women consume SPLENDA? SPLENDA can be used by all individuals, including pregnant women and breastfeeding mothers. Although SPLENDA may be used as part of a healthy pre- and post-natal diet, women who are pregnant or breastfeeding should talk to their doctor or nutritionist about the kinds of foods to eat to support their health, and their baby's health, during these special times. How low are the calories in SPLENDA? SPLENDA, the brand name for the sweetening ingredient Sucralose, has no calories. A two-teasoon serving of SPLENDA Granular or a single Low-Calorie Sweetener packet also has very few calories -- so few, that these are considered equivalent to zero under the FDA's nutrition labeling regulations. The small amount of calories in the SPLENDA Granular and Packet products come from the presence of some common, natural food ingredients in these products. These ingredients, maltodextrin, for example, give SPLENDA the necessary bulk so it can be used like sugar, but with only 1/8 sugar's calories. Both the Packet and Granular forms of SPLENDA have only 2 calories per teaspoon, while sugar has 16, and a cup of SPLENDA granular has only 96 calories, while sugar has 770. Using SPLENDA instead of sugar can therefore significantly reduce the amount of calories, sugar and carbohydrates in many of your favorite recipes. Do I have to count SPLENDA as a carbohydrate or sugar in my meal plan? No. Sucralose, the sweetening ingredient of SPLENDA, is not recognized by your body as a carbohydrate, although it tastes like, and is made from, sugar. It is not broken down by the body and, therefore, has no calories, nor will it affect your blood glucose levels. There is a small amount of calories and carbohydrate present in a single serving of either SPLENDA Granular or SPLENDA Low-Calorie Sweetener Packets (both equivalent to two teaspoons of sugar), however, the levels are so small that under the FDA's nutrition labeling regulations are considered equivalent to zero. Both the SPLENDA Granular and Packet products have only 1/8 the carbohydrate and calorie content of sugar. This means that you can use SPLENDA instead of sugar to significantly reduce the calorie, carbohydrate, and sugar content in many of your favorite recipes. What is the role of SPLENDA in a healthy diet? SPLENDA may be used as part of a healthy diet which includes a variety of nutritious foods in moderate portions. Because SPLENDA offers the sweet taste of sugar without all the calories and is ideal for cooking and baking, it helps meet your demand for good-tasting, low-calorie foods and beverages. What types of products might contain SPLENDA ? SPLENDA can be used to sweeten low-calorie versions of all food and beverage products. Internationally, over 400 products ranging from soft drinks to ice cream are sweetened with SPLENDA. The FDA has authorized the use of SPLENDA as a general purpose sweetener. In addition to all foods, SPLENDA may now be used to sweeten nutritional supplements, medical foods, and vitamin/mineral supplements. McNeil Specialty Products Company, a wholly owned subsidiary of Johnson " Johnson, developed and manufactures SPLENDA for commercial use. SPLENDA is a registered trademark of McNeil Specialty Products Company. Amino Maxx Stay in Positive Nitrogen Balance - 24 Hours a Day Whether you're dieting or gaining, there's one unchangeable rule: You need Positive Nitrogen Balance to fuel your muscle cell growth. And if you're training hard, you need extra nitrogen. Now you've got it! Just use Amino Maxx 2200 between meals and you'll stay on the 'plus' side of nitrogen balance - 24 hours a day! With Amino Maxx 2200 You Utilize and Retain More Muscle-Building Nitrogen! Science shows that peptides are the favored method for humans to boost nitrogen retention and utilization. They're simply the fastest absorbed. That's why you'll find both free-form amino acids and di- and tri-peptides in Amino Maxx 2200. Your muscles get more nitrogen - you get more muscle! BCAA Capsules BCAAs Make Up 33% of Your Muscle's Amino Acid Pool The BCAAs, l-leucine, l-isoleucine, and l-valine, are probably the most essential amino acids for athletes in training. They account for 33% of your muscle protein. Some experts believe that even moderate exercise can increase your body's need for leucine by 240%. SportPharma BCAAs increase nitrogen retention, boost protein synthesis, and protect your muscles from the stress and trauma of heavy training. These powerful - and natural - anabolics not only help you make faster gains in lean muscle - they also help you keep it! New Research Shows BCAAs Are a Direct Source of Muscle Energy! Recent research on protein balance and exercise suggests that BCAAs are used as a "direct" source of energy to a much greater extent than previously thought - as they are oxidized in the muscles and not the liver. And SportPharma BCAAs are combined in calibrated balance to ensure maximum absorption. So you get maximum results! SportPharma Creatine Monohydrate Creatine is a naturally occurring metabolite which helps recycle the body's supply of ATP for increased energy output, strength and endurance. SportPharma Creatine Monohydrate contains no fillers or additives. Ingredients: Creatine monohydrate Just-WHEY More and more people are switching to Just-WHEY. Why? To reward their bodies with the benefits of quality whey protein at a fantastic price. What are the benefits of whey protein? Compared to other proteins, whey protein is digested and absorbed into your body very quickly.(1) After working out, the glycogen (stored sugar) levels of your exercised muscles are reduced. Eating whey protein along with some carbohydrate after your workout may speed up your recovery by ensuring those glycogen levels are promptly replenished (2) A great-tasting way to do this is to add Just-WHEY to a low-fat cereal rich in complex carbohydrates, such as shredded wheat or oatmeal. Suddenly, a your favorite cold or hot cereal becomes a high-protein cereal with mouth-watering flavor. Here's another benefit of whey protein that you may not know about: Supplementing the diet with alpha-lactalbumin, one of the major proteins in whey, may enhance mood and reduce the levels of cortisol (a muscle 'unfriendly' stress hormone) in stress-prone persons.(3) Just-WHEY makes receiving this, and all of the other benefits of whey protein, simple and economical. Just-WHEY is available in 3 great flavors: Creamy Vanilla, Wild Strawberry and Decadent Chocolate. Stop spending more money than you need to on quality whey protein. Do as others are doing and make the switch to Just-WHEY now! Promax Lean Protein Bars The Fat-Destroying Power of Pepti-Lean! The Muscle-Building Power of 'Sustained-Action' Protein! The Great Taste of Promax! With the new Promax Lean Protein bar, you get it all. A leaner body. Bigger muscles. And the great taste you've come to expect from Promax. Best of all, you get the ease and convenience of the take-it-with-you-anywhere high protein bar! Promax's Lean Protein Bar - the Only Bar with Pepti-Lean You already know how Pepti-Lean blocks dietary fat and destroys existing body fat. But did you know that Promax Lean Protein is the only bar to contain Pepti-Lean? It's a fact. What's more, Promax Lean Protein provides you with a sustained-action protein formula. And it just might be the best tasting high-protein bar on the entire planet! Finally, a Great Tasting High-Protein Bar There was a time you had no choice in a bar. The price of good taste was too much sugar. The price of reduced sugar was...we'll just call it something south of bearable. Not any longer! Promax Lean Protein is the high-protein bar that gives you what other low-carb bars cannot - great taste! It is, after all, made by Promax! With a rich flavor and a smooth mouth feel, you'll find that Promax Lean Protein is the one high-protein bar that's totally satisfying. To your muscles and your taste buds. 31 grams of Protein - Only 3 Grams of Sugar** With 31 grams of sustained-action protein, Promax Lean Protein bar is the perfect solution to adding that extra protein to your diet. And with only 3 grams of sugar,** Promax Lean Protein bar is ideal for low-carb lifestyles. Remember, you get the power of fat-destroying Pepti-Lean in every bar! And best of all, Promax Lean Protein bar has all the great taste you deserve! **Based on current flavors. Lean Protein Powder Revolutionary New "Sustained-Action" Protein Formula - with Pepti-Lean - is Designed to Give You Bigger Muscles, Deeper Cuts, and a Totally Envied Body - FAST. Here's a protein formula with a totally new method of building muscle. It's called sustained-action protein. It's designed to give you more muscle in less time. Plus, each serving of SportPharma's Lean Protein powder contains the new fat-destroyer Pepti-Lean, so you get lean and ripped at the same time you're building new muscle. Sustained-Action Protein Helps Keep You in Positive Nitrogen Balance Longer SportPharma's new Lean Protein Powder extends the time your body makes muscle out of protein. Understand, your body can only build new muscle while you're in a state of positive nitrogen balance (PNB) - that's where nitrogen intake is greater than nitrogen excretion. During PNB, your body takes the available amino acid building blocks and constructs new muscle. The amount of new muscle you construct depends on the intensity and frequency of training and the duration of PNB. And SportPharma's sustained-action protein formula is specifically designed to keep you in PNB longer. "Time-Extended" Muscle Growth Means Faster Gains in Lean Mass Each protein has its own specific muscle-building "time of effectiveness." That time is dependent on each protein's molecular weight and rate of absorption. Smaller weight proteins - like whey protein hydrolisates - are quickly absorbed, but they also exit your body quickly, shortening your window of PNB (positive nitrogen balance). SportPharma Lean Protein's array of varying molecular-weight proteins, including whey and mi-cellular casein, elevate amino acid levels in your blood quickly and then help keep them there longer. The result? You get better control of positive nitrogen balance - and you simply build more muscle. SportPharma Lean Protein's Added Pepti-Lean Gives You a Powerful Fat Destroyer Adding muscle is one thing. Getting ripped and cut is another. For a really awesome body you need both. That's why you'll find a full dose of Pepti-Lean, the powerful fat-destroyer, in every serving of SportPharma's Lean Protein. Pepti-Lean helps dismantle existing body fat, assists in preventing new fat from forming, and obstructs the carb-to-fat conversion. To find out more about Pepti-Lean's fat-destroying power, read this. Scientific Background of Pepti-Lean Summary: Distinguishing Properties of Pepti-Lean SportPharma's Pepti-Lean introduces a new category of fat loss supplements. Four distinguishing factors make this possible: (1) Pepti-Lean is a supplement of nutritional origin (it is derived from protein) that accelerates the removal of body fat. Being of nutritional origin, Pepti-Lean's benefits come without the side effects sometimes associated with unnatural, non-nutrient fat-loss products (e.g., pharmaceuticals and thermogenic herbal products). (2) Unlike many existing fat-loss products, Pepti-Lean is capable of entering the bloodstream of the user following oral administration. This allows Pepti-Lean to inhibit fat gain by working not only at the gut level, but in other tissues (e.g., liver, adipose tissue) as well. Pepti-Lean users can therefore experience dramatic fat loss more quickly. (3) Pepti-Lean is composed of a proprietary blend of small protein molecules, termed peptides, obtained from the breakdown, or digestion, of naturally occurring proteins. Importantly, the combination of peptides found in Pepti-Lean is supported by human and animal research demonstrating the ability of certain such peptides to help reduce body fat and prevent fat gain (see below for more details). (4) Pepti-Lean inhibits body fat gain by interfering at several steps along the pathway to fat storage. Among others, these include the digestion and absorption of dietary fat and the conversion of dietary carbohydrate into fat. Its diverse range of biological activity enables Pepti-Lean to be used successfully with a variety of diets (e.g., carbohydrate-restricted diets, low-fat diets). Scientific Background of Pepti-Lean: How We Get Fat Ultimately, getting fat is about being in a positive fat balance. This can occur when you consume more fat than your body burns as fuel. The result is a net gain of body fat. A positive fat balance is not necessarily the result of eating too much fat per se; body fat can also accumulate when you consume more calories of any kind than you burn over time. It is well known, for instance, that a high-carbohydrate diet virtually devoid of fat can cause body fat gain in animals and humans. The human body 'burns', or oxidizes, a mixture of fuels all the time; namely, carbohydrate, fat and protein. Carbohydrate (specifically glucose) is its fuel of choice; second most important is fat, followed by protein. Thus, eating carbohydrate causes your fat-burning rate to decrease as carbohydrate takes precedence over fat in the hierarchy of fuel oxidation. This increases the risk of even a small amount of fat contained in a meal being stored as fat on the body. In addition, when you eat more calories than you burn, carbohydrate consumed in excess of needs is more likely to be converted into fat (i.e., de novo lipogenesis). Though your body's capacity to do this is very limited, when calories are consumed in excess of needs for a sustained period of time, body fat gain can result. This is more likely to occur when the capacity to store carbohydrate (e.g., as glycogen in muscle, liver) is less than optimal, as occurs when body's muscle mass is subject to the typical high-calorie, sedentary lifestyle. How Pepti-Lean Accelerates Fat Loss Losing body fat requires sustaining a negative fat balance, i.e., burning more fat than you consume. Over time this results in a net loss of body fat. As will be discussed in greater detail below, Pepti-Lean promotes a negative fat balance in several ways. Briefly, Pepti-Lean reduces the absorption of food fat, causing less to enter your bloodstream for storage in fat cells. Pepti-Lean also helps direct the fat that does manage to get absorbed away from fat cells. Thirdly, Pepti-Lean accelerates the burning of fat as a fuel. Finally, Pepti-Lean reduces the conversion of carbohydrate into fat. The end result is that daily use of Pepti-Lean effectively 'starves' your fat cells, causing them to atrophy (shrink). Pepti-Lean interferes with several steps in the fat storage pathway: (1) Dietary fat absorption: Peptides found in Pepti-Lean appear to reduce the absorption of fat from meals (Kagawa et al., 1998). All foods contain some fat. By reducing the amount of fat absorbed into the bloodstream from the gut, Pepti-Lean promotes a negative fat balance. Note that suppression of fat absorption in the gut is the mechanism of action of a number of anti-obesity drugs. Pepti-Lean may act by interfering with the enzymatic digestion of dietary fat in the gut and/or it may inhibit the transfer of digested fat across the intestine and into the bloodstream. (2) Fat partitioning/Fat oxidation: Pepti-Lean helps direct fat that does manage to get absorbed from your meals away from fat cells and toward fat-burning pathways. These include energy-liberating pathways in the liver (Okuda, 1993b) and possibly other tissues. (3) Reduced conversion of carbohydrate into fat: Pepti-Lean helps reduce the conversion of carbohydrate into fat. Thus, Pepti-Lean can be effective in accelerating fat loss on a high-carbohydrate diet. A peptide mixture similar to that found in Pepti-Lean has been found to reduce body fat gain in animals fed either a high-fat or high-carbohydrate diet (Okuda, 1993c). (4) Reduced triglyceride (triacylglycerol) levels: The combined actions of the fat metabolizing act to suppress blood triglyceride levels (Okuda, 1993a; Kagawa et al., 1998 and references therein). This exerts an anti-obesity effect by reducing the supply of fat for storage in adipocytes (fat cells). Reducing triglyceride levels also reduces the risk of cardiovascular disease and diabetes. (5) Inhibition of Adipocyte (Fat Cell) Development (Okuda, 1993d): The peptides found in Pepti-Lean have demonstrated direct inhibitory effects on adipocyte development. This could help prevent formation of new fat cells. (6) Suppression of lipogenesis (fat synthesis): The fat-metabolizing peptides have been found to suppress activities of enzymes involved in the synthesis of fat in both the liver and adipose tissue of animals (Okuda, 1993c). Pepti-Lean can be effective with many types of diets Arguably the most important distinguishing feature of Pepti-Lean is its ability to enter the bloodstream of the user and interfere with body fat gain at many different sites. It is this feature that allows Pepti-Lean to work so powerfully in such a broad variety of dietary settings. For instance, so-called 'fat-blocking' agents work by inhibiting the digestion and/or absorption of dietary fat. These may be expected to have little effect on the body composition of those following a low-fat diet. In contrast, Pepti-Lean, which can be absorbed into the bloodstream to accelerate fat oxidation and inhibit the conversion of carbohydrate into fat, can be useful in removing body fat in persons following diets low or high in carbohydrates. And because Pepti-Lean also displays 'fat-blocking' properties at the gut level, it can be effective for those consuming the typical Western high-fat diet. Origin of Pepti-Lean The food you eat is built upon three nutrients: protein, carbohydrate and fat. Pepti-Lean is composed of a proprietary mixture of specific small protein fragments, termed peptides. These peptides are formed by breaking down, or digesting, larger protein molecules derived from a variety of natural sources. Amino acids are the building blocks of protein. The peptides found in Pepti-Lean are 3-5 amino acid residues in length. The molecular weights of the peptides range from 100 to 1500. In vitro studies indicate that these fat-metabolizing peptides are for the most part not digested by gastrointestinal enzymes. Thus, the peptides can cross the gut wall and enter the bloodstream to exert fat-removing effects in the periphery (e.g., adipose tissue). Scientific Research Supporting Pepti-Lean A number of studies performed on animals have demonstrated the ability of certain proteins to reduce blood fat (e.g., triglyceride) levels. In particular, small peptides formed following the digestion of these proteins appear to have such beneficial effects in animals (Kagawa et al., 1996) and humans (Kagawa et al., 1998). These peptides are the basis of the proprietary peptide mixture found in Pepti-Lean. Anti-Obesity (Fat Loss) Effects The scientists performing the aforementioned studies thought that the peptides might be useful in reducing the risk of cardiovascular disease and obesity in humans. Studies on animals (Kagawa et al., 1996), and later, humans (Kagawa et al., 1998), showed that they were correct in their assumption. By blocking fat digestion and absorption, directing fat away from storage and toward fat-burning pathways, and reducing conversion of dietary carbohydrate into fat, these peptides can help reduce body fat, enhance lean body mass, and reduce risk of cardiovascular disease and diabetes. In a double-blind study performed on 25 healthy adults, subjects were given capsules containing 100 mg of the fat-metabolizing peptides or a placebo. Capsules were taken during or after breakfast and dinner for a total of 600 mg or 1.2 g daily (low- or high-dose groups, respectively). Both groups lost body fat by 1 month into the study. The researchers believed that the peptides prevented dietary fat from being absorbed and accelerated the breakdown of stored body fat. Some subjects experienced a loss of more than 3% in percentage body fat, with those consuming the higher dose (1.2 grams per day, spread over breakfast and dinner) tending to lose the most fat. Remarkably, the subjects were not following restricted diets; they were following ordinary eating plans containing their favorite foods. In a similar study published in the Journal of Nutrition (Kagawa et al., 1998) the fat-metabolizing peptides were found to suppress the elevation in blood fat levels typically found following a high-fat meal. The researchers also reported studies indicating that repeated consumption of the fat-metabolizing peptides stimulated the oxidation of fat in the liver. Whatever the mechanism, it was clear to the authors of the study that these peptides may be of use in preventing body fat gain. Cell studies (Okuda, 1993c) indicate that the peptides found in Pepti-Lean may suppress the formation of mature fat cells. Glycerol-3-phosphoric acid dehydrogenase (GPDH) is a marker enzyme for the differentiation of fibroblasts (a type of connective tissue cell) into fat cell precursors (pre-adipocytes). GPDH activities were suppressed by addition of the fat-metabolizing peptides (Tab.2.). Tab. 2. Effect of Fat-Metabolizing Peptides on GPDH Activities (Okuda, 1993c) Peptides (mg/ml) Before Differentiation After Differentiation GPDH (mU/mg protein) Inhibition (%) GPDH (mU/mg protein) Inhibition (%) 0 514.6+/-95.1 - 747.1+/-28.9 - 2 96.1+/-18.9 81.3 599.6+/-21.0 19.7 4 7.8+/-2.8 98.5 343.5+/-64.4 54.0 8 6.7+/-1.8 98.7 16.2+/- 4.4 97.8 The fat-metabolizing peptides also reduce fat gain when animals are fed a high-carbohydrate diet. This may be due to interference with enzymatic processes involved in the conversion of dietary carbohydrate into fat. Mice fed sucrose solutions experienced an increase in fat mass (epididymal tissue weight) (Okuda, 1993c). As shown in Figure 5, the peptides derived from bovine red blood cells (BOREP) inhibited the increase of epididymal tissue weights by sucrose feeding. Sucrose loading raised DNA levels in epididymal tissue. The peptides decreased DNA contents in epididymal tissues (Fig.6.). Fig.5. Effect of Fat-Metabolizing Peptides (BOREP) on epididymal tissue weight of mice fed on 30% sucrose solution Fig.6. Effect of Peptides (BOREP) on DNA contents in epididymal tissue of mice fed on 30% sucrose solution Pepti-Lean contains the same blend of fat-metabolizing peptides used in the studies discussed above. The effect of these peptides on body composition was investigated in a human study. A placebo-controlled, double blind method was used for this experiment to minimize the confounding effects of individual variation. The fat-metabolizing peptides were administered to the subjects orally in dosages of 0.6g and 1.2g/day for 3 months. Dietary restriction was not enforced on the subjects. Though the subjects' body weights did not change over the course of the study, the average body fat percentages were changed in a dose-dependent fashion by the peptides. Body fat 2.22+/-0.44 kg (10%) was significantly reduced by administration of 1.2 g peptides for 3 months. Lean body masses were statistically increased by intake of the peptides (Tab.1). These results suggested that the peptides decrease body fat and increase muscle and water. Tab.1. Changes of body fat and lean body mass after administration of fat-metabolizing peptides for 3 months. Groups ? Body weight (kg) ? Body Fat (kg) ? Lean Body Mass (kg) Control -0.43 +/-0.48 -0.74 +/- 0.26 0.15 +/- 0.43 Peptides 0.6g 0.08 +/- 0.29 -1.71 +/- 0.38 1.70 +/- 0.41* Peptides 1.2g -0.46 +/- 0.43 -2.22 +/- 0.44* 1.69 +/- 0.44* Values are mean +/- SEM. Each value subtracted 3 months level from initial one. *P 0.05, compared with each control value, respectively. Cardiovascular Benefits Inappropriately high levels of triglycerides (hypertriglyceridemia) and nonesterified fatty acids are a common component of obesity, insulin resistance, hypertension, and hyperlipidemia. It has been proposed that increased levels of triglycerides and fatty acids are key factors in the progression of these disorders, which suggests that normalization of these parameters could contribute to an effective therapy. When healthy volunteers were fed a fat-loaded (25 grams*) meal alongside 1 gram of a peptide mixture similar to that found in Pepti-Lean, the peptides suppressed the appearance of blood triglycerides as compared to those receiving the high-fat meal only (Okuda, 1993a). *Twenty-five grams of fat was chosen in this Japanese study for the reason that at the time of its publication, this was considered to be the fat content of the average Japanese meal. North Americans frequently consume much higher amounts of dietary fat and may therefore require more Pepti-Lean under such meal conditions. The researchers took blood samples from the volunteers at 1,2,3 and 4 hours following ingestion of the high-fat meal. Compared to the group consuming only the meal, those ingesting the meal + peptides demonstrated a reduction in serum triglycerides at each time point. These results suggest that Pepti-Lean may be useful for lowering triglycerides in borderline hypertriglyceridemic patients. Recommended Use of Pepti-Lean Research involving fat-metabolizing peptides similar to those found in Pepti-Lean suggests that it should be taken with at least 2 meals per day. Doing so can substantially reduce the risk of fat in those meals being stored as such on the body. The results can be dramatic. Indeed, human studies suggest that subjects don't require much of the fat-metabolizing peptides to see benefits. In a Japanese study, the researchers reported that the benefits of the fat-metabolizing peptides can be achieved with a smaller dose than the typical protein intake and 'stimulation of lipid metabolism [e.g., fat-burning] by continued use.' Because Pepti-Lean is essentially a nutrient, supplements containing this fat-metabolizing protein are ideal for those seeking an alternative to thermogenic stimulants (e.g., ephedrine). But Pepti-Lean can also successfully be combined with thermogenics for even more spectacular muscle enhancing, fat-burning effects. And unlike some of the benefits found with thermogenic stimulants, Pepti-Lean's fat-metabolizing properties won't wear off with time. In fact, as the studies discussed earlier indicated, repeated use produces desirable effects for those trying to remove body fat and increase lean body mass. Gender-Specific Use Recommendations To date, there is no research to suggest that women should use Pepti-Lean differently than men. Both sexes are encouraged to use Pepti-Lean in conjunction with proper exercise and diet in order to enhance body composition and reduce disease risk. Women naturally tend to have more body fat and less lean body mass (e.g., muscle) than do men. Thus, Pepti-Lean represents a safe and nutritional means by which to promote fat loss in women without the undesirable side effects sometimes associated with stimulant products. Availability of Pepti-Lean SportPharma has recently launched a new generation of body composition enhancing supplements containing the fat-metabolizing Pepti-Lean peptides: Pepti-Lean Capsules and Promax Lean Protein bars with Pepti-Lean .

Please click here for page 102.