5-methyl-7-methoxy-isoflavone (Methoxy-7) and ipriflavone in a Hydroxy-propyl Beta Cyclodextrin complexed lozenge for great absorption!
5-methyl-7-methoxy-isoflavone or methoxylsoflavone - Methoxyisoflavone may very well be the most potent legal nonhormonal anabolic compound known. This compound was developed by a Hungarian pharmaceutical giant, generally thought of as leaders in the field of isoflavone research, to combat wasting conditions. Methoxyisoflavone was originally called an "anabolically effective compound for use as a pharmaceutical or feed additive". In clinical studies, Methoxyisoflavone was tested directly against anabolic pharmaceuticals and it was concluded that identical doses of those pharmaceuticals did not exert anabolic effects stronger than Methoxylsoflavone. Further clinical trails showed that Methoxylsoflavone dramatically reduced cortisol levels while significantly increasing protein utilization, protein synthesis and nitrogen retention.
7-isopropoxyisoflavone or ipriflavone - Ipriflavone was first developed in the 1970's by a European company looking for nutrient partitioning agents that could help shuttle vital muscle building nutrients away from adipose (fat) tissue and toward proteinaceous (muscle) tissue. Numerous studies proved ipriflavone's potent anabolic effect were for real and at the same time this unique compound was able to simultaneously reduce body fat levels. Additional studies confirmed ipriflavone significantly increased protein synthesis and nitrogen retention while preventing muscle breakdown and greatly enhancing recovery, all with no negative effects to the body's endocrine system.
The use of HPBCD cyclodextrin as a improved delivery system can magnify the absorption effect of these 2 compounds as much as 10 times over oral capsules.
Dissolve 1 tablet slowly in mouth 4 times per day.
Sports One Cycloroid
Manufacturer Description: Most of you have heard about prohormones such as 4-Diol and Norandro and Nordiol. All these amazing prohormones have been clinically proven to raise testosterone. You're about to find out how stacking Cycloroid will allow you to accomplish what use to be an almost unattainable feat. This revolutionary next generation compound is sure to rock your world.
Yes, it's finally here. The ultimate combination of the most effective bodybuilding supplements ever put together in one pre-packaged kit. It's imperative that you have high levels of testosterone because it is necessary to support the anabolic (building up) processes that produce massive muscles.
These hormone precursor substances are especially effective when correctly stacked with the right enhancers. With the advent and use of Hydroxy-Propyl-Beta-Cyclodextrin (HPBCD) we have made all compounds contained in Cycloroid 100% soluble and bio-available and therefore absorb easily into your body.
Because prohormones really do work and are not some hyped up ingredient that is useless, you can assume that there has to be a down-side. If you did, you were correct. The problem is when your body uses prohormones it produces a substance called aromatase, which causes aromatization.
Aromatization is the conversion of testosterone to estrogen. This is part of the down-side. When some testosterone converts to estrogen, you end up with less testosterone, and the extra estrogen causes the body to produce and store fat. This counteracts the ripped, cut and defined condition you've worked so hard to achieve. This is where CYCLOROID is different. You can max out your body and never have to worry about increase estrogen levels. You won't loose any of your current level of definition from an unwanted increase of body fat. You'll actually reduce your fat percentage and increase your lean body mass. Here's the solution. You see there's a substance, a superflavone that occurs in nature and blocks aromatase an inhibits aramatization. It's called chrysin. Recent studies have shown that chrysin is effective at blocking aromatase. However, up until recently, chrysin would not totally absorb into your body. That's where Cycloroid is different. Sports One uses a method to help it absorb. This means that your going to achieve the most awesome results and not have to deal with the unwanted effects.
Now, one of the most important things is that you want to build muscle and burn fat. That's were Cycloroid is king. Cycloroid has a unique thermogenic formulation. Simply put, thermogenesis is the raising or increasing of the metabolism, which in turn causes fat to be burned. Fat can be reduced in two basic ways. Starvation or appetite suppression. Any experienced bodybuilder knows that is not the solution to build muscle. It is simple, you have to eat a lot of protein and good foods. Starvation or reduced food intake will result in catabolic muscle breakdown - a bodybuilder's worst nightmare. That's where Ma-Huang, Caffeine and Yohimbine work synergistically to pump up you up and increase your metabolism and thermogenic process. Cycloroid also has an incredible new compound, D- Ribose. Ribose will help regulate your insulin and increase your ATP production and help your muscles recover. You can continue to eat a balanced diet that is high in protein and low in carbohydrates and build muscle. Just ask Craig Titus and any other professional bodybuilder.
If you want to enjoy the most incredible progress possible, you should try Cycloroid. Frankly, all your ultimate gains in the gym come down to energy, training and proper nutrition. It takes a lot of energy to build muscle. Cycloroid is explosive. Massive energy and greater endurance, leaner muscle mass and increased fat loss is what will aid you to a championship physique. The exact combination contained in Cycloroid has helped Craig perform better in the gym. That's where it counts. Give Cycloroid a try.
Two lozenges contain:
Tribulus Terrestris: 250 mg
4-Androstenediol: 25 mg
Norandrostenedione: 15 mg
Nor-4-Androstenediol: 8 mg
Ma-Huang: 25 mg
DL-Norephedrine: 25 mg
Chrysin: 50 mg
Caffeine: 90 mg
Yohimbe: 2.5 mg
Vitamin C: 100 mg
Zinc: 5 mg
Fortified with D-Ribose
* Pro-hormones are not for use by children, teenagers, pregnant or nursing women. Do not use this product if you have breast, uterine, ovarian or prostate problems. If you are under medical supervision, consult with your physician before taking product. Too much testosterone before being fully grown could cause premature closure of the growth plates which control the growth of the body's long bones. This could stunt growth. Do not take pro-hormones until you have reached your full growth potential. Cycling Recommendations: We recommend that you take three weeks off for every six weeks of taking pro-hormones to prevent your body from adjusting to the exogenous (external) source of hormones. As always, consult your physician before taking any product that may alter hormone levels.
U.S. Federal Trade Commission Warning: This product contains steroid hormones that may cause breast enlargement, testicle shrinkage, and infertility in males, and increased facial and body hair, voice deepening, and clitoral enlargement in females. Higher doses may increase these risks. If you are at risk for prostate or breast cancer you should not use this product.
# This product contains ephedrine alkaloids. Netrition recommends that you start with less than the recommended dosage of products containing these central nervous system stimulants. Take it with a meal to test your tolerance of this product before increasing to the recommended dosage. Do not take more than one product at a time containing any central nervous system stimulants like ephedra or caffeine. If you are taking any prescription drugs or over the counter medicine, check with you physician prior to use. If you experience bad side effects, discontinue use immediately and consult a physician.
U.S. Federal Trade Commission Warning: This product contains ephedra or ephedrine. Taking more than the recommended serving may result in heart attack, stroke, seizure or death. Consult a health care practitioner prior to use if you have high blood pressure, heart or thyroid disease, diabetes, difficulty urinating, prostate enlargement, or glaucoma, or are using any prescription drug. Do not use if you are taking a MAO inhibitor or any allergy, asthma, or cold medication containing ephedrine, pseudoephedrine, or phenylpropanolamine. Discontinue use if dizziness, sleeplessness, loss of appetite, or nausea occurs.
Di-Indolin (also called diindolymethane or DIM)
Non-Steroidal, Estrogen Management System
Hormonal management through clearance of estradiol " testosterone support
Antioxidant support through production of estrogen metabolites " progesterone
Far more effective than Chrysin or Soy Isoflavones
PROHORMONES AND THE ESTROGEN FACTOR
By Jerry Brainum
The introduction of prohormone supplements, capable of being actively converted into testosterone by naturally-occurring body enzymes, has made the term "anabolic supplement" a reality. Supplements such as androstenedione and others are termed "prohormones" because they serve as direct precursors for testosterone synthesis in the body. However, a less publicized effect of such supplements is their tendency to also be converted into estrogen.
Estrogen, like all hormones, has its good and bad effects. Though frequently termed a "female" hormone, this label is a misnomer, since it's also produced in men--though in far smaller amounts compared to women. The reason why men produce estrogen isn't completely understood, although some evidence indicates that it may play a role in sperm maturation. However, most of the effects of estrogen in men are negative, especially if the male hormonal scale tips more in the direction of estrogen compared to testosterone. What could tip this sex hormone scale in favor of estrogen in a man? Several factors may induce this condition. For example, testosterone is converted into estrogen by way of a ubiquitous enzyme located throughout the body, but especially in peripheral fat tissue called aromatase. Thus, just having abundant fat stores in the body increases the risk of having higher estrogen levels in men, and women, too, for that matter.
Normally most of the circulating testosterone in the blood plasma are bound to liver-produced proteins, such as sex-hormone binding globulin (SHBG) and to a lesser and weaker extent, albumin. But only the free or unbound testosterone (about 2% of the total amount in plasma) in active in the sense that it can interact with cellular androgen receptors.
When prohormone supplements are converted into testosterone by various enzymes in the liver and other tissues, they circulate in the blood as free and bound testosterone. As such, they are subject to conversion to estrogen whenever the enzyme aromatase is encountered. As the estrogen levels rise from this conversion, the testosterone/estrogen ratio (T/E ratio) tips toward estrogen. When that happens, several negative events related to higher body estrogen levels in men begin to occur. These estrogen-related effects include possible gynecomastia or male breast development. This is commonly seen in many athletes who use anabolic steroid drugs capable of being aromatized, such as testosterone injections.
Another possibility is benign prostatic hyperplasia (BPH) or prostate gland enlargement. Research shows that BPH results from a combined effect of a testosterone byproduct called dihydrotestosterone (DHT) and estrogen (0). Estrogen metabolites offer protective effects for women against cardiovascular disease onset presumably through the antioxidant activities of the 2-hydroxy metabolites.
In men, the failure to metabolize estrogen has been linked to reverse effects, including that of promoting increased internal blood clotting associated with both heart attacks and strokes. This was shown in many studies, including the long-term Framingham Heart study. In that study, men with the highest estradiol or unmetabolized estrogen levels showed the greatest risk of early heart attack.
There is a way, however, to harness the benefical cardiovascular effects of estrogen for men, which I'll reveal later. Recognition of the tendency for free testosterone to convert into estrogen has led to a search for natural alternatives to offset this notable problem. Drugs that inhibit aromatase, such as Testlac and Arimidex, are sometimes prescribed to for breast cancer preventive effects in women. But such drugs are extremely expensive, hard to obtain, and may impart undesired side effects of their own.
An over-the-counter supplement called chrysin, classified as a flavonoid, is found naturally in plants, and is often suggested as a natural, safe supplement to inhibit the aromatase enzyme that converts testosterone into estrogen. However, while the potency of chrysin is comparable to potent drugs such as Cytadren that also inhibit aromatase, these effects have thus far been shown to occur only in test tube studies. No one has yet determined the effectiveness of chrysin inhibition of aromatase in the human body. Some controversy even exists as to how well chrysin is absorbed into the body.
Obviously a substance that could curtail or even nullify some of the deleterious effects of estrogen would benefit both men and women. While women do naturally produce more estrogen that men, it's also true that in excess, estrogen has cancer-promoting effects in women, particularly in the breasts and reproductive tract. Such a estrogen-modifier would have to be safe, and not interfere with the beneficial effects of other hormones, such as testosterone. The question is: does such as substance exist? The vegetable cure Scientists have been aware for over a decade that certain foods contain naturally-occurring protective substances. Many such substances occur in plants and vegetables, and are often collectively referred to as phytochemicals or literally "plant chemicals." Cruciferous vegetables, such as broccoli, cabbage, and cauliflower contain some of the most potent protective phytochemicals yet discovered. These include sulforaphane, which works to prevent cancer by inducing a potent detoxifying enzyme system in the liver called phase-2 enzymes.
Another cruciferous phytochemical is called indole-3-carbinol(I3C). IC3 acts as an estrogen antagonist (2). Numerous studies published during the past decade conclusively show that I3C converts estrogen to safe metabolites , while also promoting estrogen inactivation and excretion (3). The dietary indoles found in cruciferous vegetables modify estrogen and promote its conversion into beneficial forms, such as 2-hydroxy and 2-methoxyestrogen (4). The synthesis of these "good" estrogens tends to decrease the production of "bad" estrogens that are linked to disease processes, including various cancers in both sexes (5).
Subsequent research revealed that indole-3-carbinol isn't the primary active ingredient that promotes beneficial estrogen synthesis. The process is actually a cascade effect, beginning with a phytochemical in cruciferous vegetables called glucosinolate, which is converted by enzymes into indole-3-carbinol. The indole-3-carbinol, in turn, is converted into the true active ingredient, diindolymethane (DIM) (6). Pure DIM was initially used in supplement form and given to animals in 1987 (7). Animal studies showed it to be both effective and nontoxic. When animals were exposed to carcinogens that initiated breast and colon cancers (8), the addition of DIM inhibited such cancers . Further research revealed that the mechanism behind these anticancer effects of DIM included reducing estrogen cell receptor activity (9); promotion of the "good' 2-hydroxy estrogens (10); and through supporting selective apoptosis, or programmed cell death, which allows the body to remove damaged cells prone to cancer (11).
Providing DIM to humans leads to an increased ratio of good 2-hydroxy estrogens to "bad" 16-hydroxyestrone. In fact, human studies showed that DIM resulted in a 75% increase in good estrogens with a 50% decrease in bad estrogens linked to disease onset. Other studies show that low levels of the beneficial 2-hydroxy estrogens are linked to breast cancers in both men (12) and women (13); uterine cancer (14); cervical cancer; and system lupus erythematosus (15), an autoimmune disease more common in women. Many previous risk factors for breast cancer development, such as obesity, high fat diets, and diets lacking omega-3 fatty acids are also characterized by a low-level 2-hydroxy synthesis in the body (16).
Since indole-3-carbinol (I3C) is capable of neutralizing excess estrogen and promoting its excretion, some supplement companies have incorporated I3C into their proprietary prohormone formulas. This, however, isn't effective. First, I3C is highly unstable and has a poor shelf life. Odds are good that any supplement containing this substance doesn't have much to begin with, and even less by the time a consumer purchases it. In addition, I3C, as noted, isn't the active chemical anyway; it's instead, DIM. I3C is converted into DIM through a process involving gastric hydrochloric acid (HCL). If a person is deficient in HCL, as commonly occurs in the elderly, I3C won't effectively convert into DIM. In contrast to I3C, DIM is highly stable, doesn't need any conversion in stomach acid, and is by far the most active phytochemical in promoting the synthesis of good, protective estrogens such as 2-hydroxyestrone (17). One problem does exist, however, with DIM: it's not soluble in water in its usual crystalline form. As such, it requires a special delivery system in order to be effective for supplemental purposes. Such a system exists in a special supplement called Diindolin.
Diindolin contains DIM associated with a special matrix that improves absorption. The daily usage of a 300 milligram dosage of Diindolin approximately equals the DIM obtainable from 2-4 pounds of raw broccoli. This supplement is clearly useful not only for people that just don't like cruciferous vegetables such as broccoli, but also don't want to eat several pounds of it each day to ingest beneficial levels of DIM.
By increasing the levels of beneficial 2-hydroxy estrogens, the testosterone/estrogen ratio is increased in favor of testosterone. More importantly from an anabolic point of view, the level of free testosterone rises in the blood with use of DIM. The mechanism behind this is that 2-hydroxy estrogens have a greater binding affinity for the blood proteins that "lock up" testosterone in the blood. Thus, these plasma binding proteins instead latch on to 2-hydroxy, leaving greater levels of free testosterone, including that produced through the use of supplemental prohormones. The 2-hydroxy estrogens promoted by DIM usage also increase testosterone synthesis through another mechanism. Estrogen, even more than testosterone itself, incurs a negative hormonal feedback loop to the pituitary gland, where the rate-limiting gonadotropin for testosterone synthesis, luteinizing hormone (LH) is synthesized and released. What this means is that high blood levels of estrogen, as may occur through aromatization of free testosterone, turn off the release of LH from the pituitary gland. This leads to a vicious biochemical cycle characterized by an imbalance between testosterone and estrogen in favor of the latter. These events, however, are nullified by 2-hydroxy, which doesn't provide the negative feedback message to the pituitary induced by estrogen. The net effect is greater testosterone synthesis in the Leydig cells of the testes, as well as lower levels of bad estrogen and all the effects that go with it. DIM differs from other natural substances currently touted to decrease estrogen levels, such as the soy isoflavones, genistein and diadzen. DIM, while promoting the synthesis of beneficial estrogens, such as 2-dehydroxy, isn't itself a phytoestrogen or an estrogen mimic as are the soy isoflavones. Thus, there is no danger of a paradoxical estrogen-agonist or pro-estrogen effect with DIM as can possibly occur in some cases with soy isoflavones. Diindolin also helps to burn fat through extending the activity of catecholamines, such as epinephrine and norepinephrine. These hormones help the body oxidize fat through interacting with beta-adrenergic fat cell receptors. This leads to an enzymatic cascade resulting in the release of free fatty acids into the blood. However, catecholamines are rapidly degraded by an enzyme called catechol-O-methyl transference (COMT). This same enzyme also metabolizes 2-hydroxy estrogens. An increase in 2-hydroxy estrogens, such as that induced by Diindolin, will promote a competitive inhibition effect with the catecholamine and COMT, leading to less rapid breakdown of catecholamines and thus enhanced fat mobilization. The implications of this process are that Diindolin will serve to potentiate the increased catecholamine secretion that normally occurs during exercise. It will also provide synergistic fat oxidizing effects when combined with a ephedrine-caffeine stack, since this stack works by also increasing the release of catecholamines.
Keeping DHEA honest DHEA, an adrenal androgen, was the first of the prohormone supplements to be marketed. The problem with DHEA, however, is that it isn't as direct a precursor for conversion into testosterone as is the supplements released later, such as androstenedione. DHEA, while capable of being converted into testosterone, can also take divergent pathways, such as conversion into estrogen or DHT. This is particularly true in men under age 40. Since DHEA also offers various health benefits, such as a heightened immune response and increased insulin sensitivity, the problem of possible conversion into estrogen by way of aromatase enzyme is a daunting one.
Diindolin can once again offer benefits by promoting the conversion of any estrogen produced as a result of DHEA usage into the beneficial 2-dehydroxy form, which if anything, would provide synergistic health benefits with DHEA usage. As noted earlier, Diindolin, through increasing 2-hydroxy synthesis, blunts the effects of estrogen in promoting prostate enlargement. It is synergistic with other phytochemicals that prevent prostate enlargement, such as saw palmetto (which blocks conversion of testosterone into DHT), green tea, pygeum africanum, and stinging nettle.
Diindolin may also increase insulin response. By potentiating catecholamines, Diindolin can increase carbohydrate clearance and "reset" the insulin system to a lower starting point. This effect, in turn, increases the response of insulin to high glycemic carbohydrates or simple sugars. Since such simple sugars are needed to promote uptake and absorption of creatine into muscle through a insulin-stimulated muscle creatine uptake carrier, the increased insulin response promoted by Diindolin serves to increase creatine supplemental efficacy. Diindolin also may increase workout recovery. Studies show that estrogen appears to limit muscle damage induced by intense training. The damage may be incurred by increased free radical release from the upgraded oxygen intake typical during exercise. These free radicals damage cell membranes, leading to an inflammation discernable as muscle soreness.
One of the good things about estrogen is that it is a potent free radical quencher. Evidence shows that you can obtain this same protective effect of estrogen minus the negative aspects with 2-hydroxy estrogen metabolites promoted by Diindolin. Studies show that dietary antioxidants, such as vitamin E, increase exercise recovery by minimizing the inflammatory effects of free radical release during exercise. The 2-hydroxy estrogens are even more potent in their free radical-quenching effect than vitamin E. Thus, by relieving muscle inflammation after exercise, Diindolin may speed exercise recovery. Add it all up and you can only draw one conclusion: the future of DIM or more precisely, Diindolin, looks bright!
GP2 - Glutamine Peptides
Manufacturer Description: Advanced Protein and Creatine Cell Volumizing Glutamine Peptide System
GP-2 is designed to be added into a protein or carbohydrate drink. A recent preliminary research study has shown that glutamine peptides dramatically improves the effects of protein and creatine products. Glutamine peptides are far superior for improved nitrogen balance over free form L-Glutamine.*
GP-2 is the real thing, no flavoring, colors or any other ingredients have been added.
Now comes in a 3-week cycle instead of 2-weeks! 50% more Medroid for free!
Medroid 3.0 now has Methoxyisoflavone and Ipriflavone added!
Take the following capsule in the early morning:
Green White colored capsule:
250 mg Tribulus Terrestris
40 mg Methoxyisoflavone
250 mg Tribulus Terrestris
16 mg Ipriflavone
Take the following two capsules 60-90 minutes prior to training:
Solid White colored capsule
100 mg Androstenedione
100 mg Acetyl L-Carnitine
100 mg 4-Androstenediol
Red/White colored capsule
334 mg Ma Huang herb extract standardized for 20% Ephedra Alkoloid
50 mg Green Tea Leaf extract
White Willow Bark
Take the remaining Post-Training capsule 30 minutes after training:
Blue/White colored capsule
50 mg 19-Nor-4-Androstenediol
100 mg 19-Norandrostenedione
Warning: Prior to using this product you should seek professional medical advice from a licensed physician. Anyone with known health problems should not use this product. Do not use if you are pregnant or lactating or if you have high blood pressure, heart disease, diabetes, prostate enlargement or if you are taking a MAO inhibitor or any other prescription drug. Reduce or discontinue use if nervousness, tremor, sleeplessness, loss of appetite, or nausea occur. Not for children under 18. Store in a cool dry place away from children.
Sports One ZMA Blast
Sports One ZMA is sourced from Scientific Nutrition for Advanced Conditioning (SNAC). Studies show that by supplementing your diet with specific amounts of zinc and magnesium, you can elevate testosterone levels by as much as 30 percent. Balco Labs has conducted research to determine the exact amount of zinc and magnesium required to replenish an athlete's stores of these precious minerals. Their studies have just been accepted for publication in Sports Medicine, Training, and Rehabilitation Journal. Furthermore, Balco Labs has conducted exhaustive tests with 21 professional bodybuilders and most of the Denver Broncos football team, and all their findings have confirmed Balco Labs' theories. Based on their findings, Balco Labs developed a supplement, called "ZMA." They've also been able to determine that the best dose is 30 mg of zinc and 450 mg of magnesium taken once per day (three capsules taken between dinner and bed time). 90 Capsules per bottles.
Each Capsule Contains:
Zinc: 10mg (Monomethionine/Asparate)
Magnesium: 150mg (Aspartate)
Vitamin B-6: 3.5mg
Suggested Use: Three Capsules Daily for Men and Two Capsules Daily for Women Between Dinner and Bedtime as a Dietary Supplement or as Recommended by a Physician.
Zinc and magnesium are of vital importance to optimal performance:
A deficiency decreases muscle strength and endurance. Zinc is an anabolic element and promotes healing, tissue repair, and muscle growth. Zinc also increases the effect of Insulin-Like Growth Factor 1, Growth Hormone, and Testosterone. In addtion, many of the enzymes that prevent the buildup of lactic acid (the "fatigue acids") require zinc.
A deficiency decreases oxygen delivery to muscle tissue. Magnesium promotes muscle strength, endurance, and relaxation. Magnesium also activates enzymes necessary for the metabolism of carbohydrates and amino acids.
The body's maximum daily release of growth hormone occurs about 90 minutes after going to sleep. Both zinc and magnesium increase the effect of growth hormone. Zinc also promotes the anabolic effect of testosterone, and magnesium increases muscle relaxation. Healing, tissue repair, and muscle growth are maximized during sleep. This is the reason it is recommended that ZMA be taken between dinner and bedtime.
Benefits received by utilizing ZMA in conjunction with an effective exercise program can include:
Increased muscle strength and endurance.
A decrease in muscle cramps and pulls.
Faster healing and recovery from injuries.
Improved concentration and alertness.
Decreased water retention.
Deeper relaxation during sleep.
ZMA is an advanced formulation designed to significantly enhance strength, endurance, healing,recovery, and growth.
Through an extensive search of worldwide medical research data, we discovered that rigorous exercise and stress result in significant body losses of zinc and magnesium.
For example, in a study called "Serum Zinc in Athletes in Training," blood (serum) zinc was detrmined in 160 training athletes (103 males and 57 females). In 23.3% of the male and 43% of the female athletes, serum zinc was significantly below "the normal range."
Another example is astudy called "Strenuous Running." The runner's daily urinary losses of zinc were 50% greater on a run day compared to a nonrun day.
In addition, in a study called "Biochemical Indices of Selected Trace Minerals in Men: Effect of Stress," blood (plasma) levels of zinc and other trace minerals were determined in 66 men before and after a five-day period of sustained physical and psychological stress. Zinc levels decreased by 33%.
Another study called "Magnesium, Zinc and Copper Status of 270 US Navy Sea, Air and Land(SEAL) Trainees" conducted by the US Department of Military Medicine showed that the dietaryintakes of over a third of the SEAL trainees were below the Recommended Daily Allowances for Magnesium and Zinc. The blood serum concentrations of magnesium and zinc were also significantlybelow the "normal range" for 23% and 24% of the trainees, respectively.
These zinc and magnesium losses can have a significant effect on strength and endurance. For example, in a double-blind cross-over study called "Zinc and Muscle Strength and Endurance," therapeutic administration of zinc significantly improved muscle performance.
In another study called "Effects of Magnesium Supplementation on Strength Training in Humans," peak quadricep torque (leg press) measurements were made before and after a seven-week strength training program. The strength of the magnesium-supplemented group significantly increased by 26%, compared to only 10% for the placebo groups.
A Novel Zinc and Magnesium Formulation (ZMA) Increases Anabolic Hormones and Strength in Athletes
L. R. Brilla, Western Washington University, Bellingham, WA 98225, and V. Conte, BALCO Laboratories, Burlingame, CA 94010.
A double-blind, randomized study was conducted to determine the effect of a novel zinc and magnesium formulation (ZMA) on anabolic hormone levels and strength in athletes. Members of the University football team (n=27) had blood collected at the beginning and end of an 8 week period of intensive training.
Subjects were supplemented with ZMA (n=12) or placebo (n=15) for the 8 weeks. The ZMA group took 3 capsules nightly that contained a total of 30 mg of ZN as monomethionine/aspartate, 450 mg of Mg as aspartate and 10.5 mg of vitamin B-6.
The plasma Zn and Mg levels increased in the ZMA group by 29.1% (.804 to 1.038 mcg/ml) and 6.2% (19.43 to 20.63 mcg/ml), respectively, while levels decreased in the placebo group by 4.4% (.836 to .799 mcg/ml) and 9.2% (19.68 to 18.04 mcg/ml), respectively.
The total and free testosterone levels in serum increased in the ZMA group by 32.4% (567.9 to 752.7 ng/dl) and 33.5% (132.1 to 176.3 pg/mL), respectively, in contrast to the placebo group which decreased by 10.5% (588.8 to 526.8 ng/dL) and 10.2% (141.0 to 126.6 pg/mL), respectively.
The serum IGF-1 levels increased in the ZMA group by 3.6% (424.2 to 439.3 ng/mL) and decreased in the placebo group by 21.5% (437.3 to 343.3 g/mL).
All comparisons were statistically significant (P 0.001). Pre and post isokenetic strength determinations in newton meters were made using a Biodex dynamometer.
Subjects (ZMA n=10; placebo n=11) were measured for maximum quadricep strength on the right leg at 180 degrees per sec (strength) and 300 degrees per second (functional power). The ZMA strength group change at 180 degrees per second was 11.6% (189.9 to 211.8) compared to the placebo group change of +44.6% (204.2 to 209.1) and the ZMA group change at 300 degrees per sec. was +18.2% (316.5 to 373.7), in contrast to the +9.4% (369.5 to 404.3) for the placebo group (P 0.05).
These findings suggest that nightly supplementation with ZMA significantly increases Zn and Mg levels, anabolic hormone levels as well as strength and power in athletes.
Sports Medicine, Training and Rehabilitation Journal, November 1998 (in press)
Please click here for page 104.